We further showed induction of CXCL12 in HMEC-1 cells by either mixture of pro-inflammatory cytokines (IL-17A, IL-22, TNF, IL-1α, and oncostatin M) (Supplementary Fig. 7e), or serum from active psoriasis patients (Supplementary Fig. 7f). Here, CXCL12 is linked to psoriasis.