The EGFR pathway prompts OSCC cell proliferation, metastasis, invasion, and apoptosis resistance.93 Radiation triggers the translocation of EGFR into the nucleus, where it functions as a transcription factor and leads to radiotherapy resistance in oral cancer.94 The EGFR also interacts with other receptors, such as Axl, increasing its carcinogenic potential on the mucosal surface of the oral cavity.95 The gene discussed is EGFR; the disease is lip and oral cavity carcinoma.