Without considering fertility results, when comparing the two groups of “control and PCOS”, increased levels of STAT3 (1.6-fold),RHOA (1.4-fold), GAS5 (3.3-fold), and LINC01116 (4.5-fold) genes were found in PCOS patients, and the difference was significant (STAT3 P=0.0144) (RHOA P=0.001) (GAS5 P<0.0001) (LINC01116 P<0.0001) (Figure 6A, C, E, G). The gene discussed is GAS5; the disease is polycystic ovary syndrome.