In the PCOS patients, there was a significant positive correlation of RHOA gene expression with GAS5 (r = 0.403, P=0.022) and STAT3 (r = 0.369, P=0.038) and also a significant positive relationship between the GAS5 gene and LINC01116 gene expression (r = 0.540, P=0.001) (Figure 8B). This evidence concerns the gene RHOA and polycystic ovary syndrome.