As shown in Fig. 6F and Fig. S17, ZNF469 expression was positively correlated with PRRX1 expression levels in breast invasive carcinoma (BRCA) (r^Pearson = 0.62, P < 0.001), which suggests that ZNF469 may be associated with tumor metastasis, affecting breast cancer progression, and may provide useful information for early clinical diagnosis, new therapies, and targeted treatments. This evidence concerns the gene PRRX1 and breast cancer.