When compared to SLE-PBMC only recipients (Control-single), a single injection of CD4+CD25+CD127low UCB-Tregs (Treatment-single) led to an improvement in weight gain (Figure 3B) and survival (63 median survival days for the Control-single group and 90 median survival days for the Treatment-single group, Figure 3C). Here, CD4 is linked to systemic lupus erythematosus.