Additionally, CD4+CD25+CD127low UCB-Tregs also decreased several inflammatory cytokines implicated in lupus pathogenesis both in vitro and in vivo, including IP-10 (51), TNF-α (52), IL-6 (53), IL-17A (54), and IL-1 (55). The gene discussed is IL17A; the disease is systemic lupus erythematosus.