(vi) sCD40L: Significantly higher sCD40L levels of 241 ± 1 pg/ml at 3 days and 327 ± 24 pg/ml sCD40L at 7 days were secreted by SLE-PBMCs when compared to CD4+CD25+CD127low UCB-Tregs alone levels of 29 ± 8 pg/ml and 13 ± 3 at the corresponding time points (p < 0.0001). The gene discussed is CD4; the disease is systemic lupus erythematosus.