INS and type 2 diabetes mellitus: Moreover, this chromatin accessible region was recently predicted to regulate the expression ofDGKB in human beta cells with high-insulin content (Chiouet al., 2021), which is further supported byin vitro data demonstrating the T2D risk haplotype at rs17168486 influenced luciferase expression in 832/13 and MIN6 cells (Viñuelaet al., 2020).