Based on univariate and multivariate analyses, we included the independent influencing factors of RC-specific death, including Age, Marriage, Race, Sex, ICD-O-3Hist/Behav, Grade, AJCC stage, T stage, N stage, Surgery, Examined LN, RX SUMM-SURG OTH, Chemotherapy, CEA, Deposits, Regional nodes positive, Brain, Bone, Liver, Lung, Tumor size, and Malignant. The gene discussed is CEACAM5; the disease is neoplasm.