CD8A and neoplasm: As shown in Fig. 9C, CYFIP2 expression had significantly negative associations with tumor purity (r = − 0.149, P = 9.29e-04) and significantly positive correlations with infiltrating levels of B cell (r = 0.388, P = 8.01e–19), CD8 + T cell (r = 0.12, P = 7.93e–03), CD4 + T cell (r = 0.305, P = 6.78e–12), macrophage (r = 0.075, P = 1.00e–1), neutrophil (r = 0.106, P = 1.94e–02), and dendritic cell (r = 0.218, P = 1.22e–06).