The expression correlations between CYFIP2 and immune microenvironment scores in different cancers were plotted by heatmap in Fig. 11A. The results revealed that the stromal score, immune score and estimate score of ACC, GBM, KIRC, LGG, SARC, and UCS were negatively associated with CYFIP2 expression levels. The gene discussed is CYFIP2; the disease is glioblastoma.