As shown in Fig. 7B, CYFIP2-interacting genes were highly involved in a series of LUAD and immunity related pathways such as Ras signaling pathway, PI3K/AKT signaling pathway, VEGF signaling pathway, chemokine signaling pathway, EGFR tyrosine kinase inhibitor resistance, B cell receptor signaling pathway, T cell receptor signaling pathway, HIF-1 signaling pathway, and non-small cell lung cancer. This evidence concerns the gene AKT1 and non-small cell lung carcinoma.