CASP3 and Cerebral ischemia: A study [47] on EA intervention in middle cerebral artery occlusion (MCAO) rats from cerebral ischemia–reperfusion injury showed that EA decreased the pro-apoptotic proteins Bax and caspase-3, increased the anti-apoptotic protein Bcl-2, inhibited the transcriptional activity of NF-κB and TRPV1 expression.