In addition, serum CASC7 showed an AUC of 0.709 (95% CI: 0.583 to 0.836) to discriminate between tumor size ≥ 5 and < 5, and an AUC of 0.719 (95% CI: 0.604 to 0.834) to discriminate between patients with TNM III + IV from those with TNM I + II. Here, AGO2 is linked to neoplasm.