In both TCGA-CESC and FUSCC cohorts (Fig. 1A, B), the expression pattern of dsRBPs-related subtypes or genes is consistent: ADAR and DDR subtypes are significantly downregulated in tumor tissues; whereas helicase, OAS RNAseL, PKR and RLR subtypes are significantly overexpressed. Here, SMOC1 is linked to neoplasm.