Interestingly, leukemia-associated pathways that were regulated by ERG in murine fetal liver-derived HSPCs (Hoxa9-Meis1, CBFA2T3, and repression of myeloid differentiation genes) were ranked at the leading edge of gene sets that were significantly perturbed after HDAC3 inhibition (Fig. 7D). This evidence concerns the gene HDAC3 and leukemia.