HD, a hereditary neurodegenerative disease due to an abnormally high number of CAG repeats in the huntingtin (HTT) gene,55 has also been linked to ferroptosis in animal models.56 Excess iron remains a major cause of oxidative stress in neurons, which directly induces ferroptosis during the pathogenesis of HD.57 Interestingly, similar to PD, reduced levels of GSH have also been observed in HD.58 Together, these findings suggest that ferroptosis may be involved in the pathogenesis of HD. The gene discussed is HTT; the disease is Huntington disease.