Recently, baicalein was shown to prevent ferroptosis in erastin-treated PANC1 cells (a human pancreatic cancer cell line) by reducing ferrous iron, inhibiting GSH consumption, and inhibiting GPX4 degradation, thereby suppressing lipid peroxidation.297 These results suggest that baicalein may prevent ferroptosis-associated tissue damage. Here, GPX4 is linked to familial pancreatic carcinoma.