The semi-synthetic derivative and major active metabolite of artemisinin, dihydroartemisinin (DHA), has been shown to increase ferroptosis in lung cancer cells by inactivating the PRIM2/SLC7A11 axis,285 as well as in head and neck cancers286 and glioblastoma cell lines287 by inhibiting GPX4. This evidence concerns the gene GPX4 and glioblastoma.