In the phenotype scanning phase, based on the genome-wide significance threshold (P < 5 × 10−8), we observed KDELC2 to be associated with various cancers, such as breast cancer, renal cell carcinoma, and uterine leiomyoma, which suggested that KDELC2 may be deficient in specificity for PCa diagnosis. This evidence concerns the gene POGLUT3 and posterior cortical atrophy.