POGLUT3 and hereditary clear cell renal cell carcinoma: In the phenotype scanning phase, based on the genome-wide significance threshold (P < 5 × 10−8), we observed KDELC2 to be associated with various cancers, such as breast cancer, renal cell carcinoma, and uterine leiomyoma, which suggested that KDELC2 may be deficient in specificity for PCa diagnosis.