SNHG6 and cancer: A negative correlation was established between the expression of SNHG6 and p21; when SNHG6 was artificially silenced using small interfering RNA (siRNA) in specific NSCLC cell lines, a notable decrease in SNHG6 levels was observed, leading to a reduced cell viability; additionally, upregulation of SNHG6 was linked to increased cancer cell proliferation and the formation of malignant phenotypes.