To extend our findings to human samples, the protein levels of WDR6 and FASN, as well as liver TAG contents, were detected in 20 liver tissue samples collected from individuals with hepatobiliary tumours who underwent liver resection in Shandong Provincial Hospital between March 2016 and April 2021 (Supplementary Data Fig. 5a). Here, WDR6 is linked to hepatobiliary neoplasm.