SDC4 and idiopathic pulmonary fibrosis: Moreover, BALFs from BLM-treated mice or IPF patients stimulated ECM invasion of LFs56,57, shown to be attenuated upon silencing LPAR1, EGFR and FGFR2 receptors56, or by interfering with Sdc4-CXCL10 interactions57, suggesting additional signals that could modulate LF invasion.