COL1A1 and pulmonary fibrosis: Increased Tks5 mRNA levels, correlating with Col1a1 mRNA levels, were also detected in the lung tissue of mice post bleomycin (BLM) administration (Fig. 1g, h), a widely used animal model of pulmonary fibrosis;23–25 immunostaining localized Tks5 in the alveolar epithelium and fibrotic areas (Fig. 1i), as in human patients.