AIFM2 and hepatocellular carcinoma: Unexpectedly, no significant effects on glucose uptake and lactate production were observed when AIFM2 was knocked down or overexpressed, whereas oxygen consumption rate, OXPHOS complexes activities, and ATP production were positively regulated by AIFM2 in HCC cells, indicating that AIFM2 promotes mitochondrial oxidative metabolism in HCC cells.