AAV8‐shNanog infection successfully suppressed NANOG expression as shown by non‐detection of hepatic Nanog mRNA, NANOG+ hepatocytes, and POU2F2+ NANOG+ hepatocytes at this time point (Figure 4B,C), but it did not affect POU2F2+ hepatocytes production (Figure S6A, Supporting Information). This evidence concerns the gene POU2F2 and infection.