After intersection of these two gene sets, we firstly identified eleven genes (TRPC5, TENM1, PDZRN4, NELL2, FRMD3, APOE, ARMCX3, DMD, APOC1, SLC35F3, AUTS2) highly expressed at both the tumor cell and tissue levels (Fig. 6A). The gene discussed is FRMD3; the disease is neoplasm.