In line with previously published CRISPR KO screens in mouse and human tumor cells, we identified genes involved in autophagy, IFN-γ and TNF-α signaling pathway (Kearney et al., 2018; Lawson et al., 2020; Patel et al., 2017; Vredevoogd et al., 2019). This evidence concerns the gene IFNG and neoplasm.