Three normal human lung tissue cell lines (Mrc5, BEAS2B, and CCD‐19Lu) were selected as the control group, and different NSCLC cell lines (A549, H1299, Calu‐1, Calu‐3, H460, and HCC827) were used to verify GPR37 expression. The gene discussed is GPR37; the disease is non-small cell lung carcinoma.