PLXDC2 and male infertility: Within these breakpoint regions, we identified twelve potentially interrupted genes, two of which are related to male infertility and embryo transport (Camprubí et al., 2016; Bianchi et al., 2021), namely, FOXK2 in the 17q regions of patient 02 and PLXDC2 in the 10p regions of patient 03 (Table 2).