Generally, JunB regulates cell cycle, differentiation, senescence, metabolism, and metastasis of tumor cells to affect tumor progression (Konishi et al., 2008; Santaguida et al., 2009; Liu et al., 2021; Wutschka et al., 2021; Perez-Benavente et al., 2022). This evidence concerns the gene JUNB and neoplasm.