Noteworthily, JunB promotes the progression of Th2-mediated autoimmune diseases, such as asthma (Hartenstein et al., 2002) and skin allergy (Fang et al., 2002), and Th17-mediated autoimmune encephalomyelitis and colitis (Carr et al., 2017). The gene discussed is JUNB; the disease is autoimmune disease.