The results demonstrated that i) among three aneurysm models, the numbers of upregulated genes in three ER stress TF potential target genes in the aorta from BAPN-Ang II AAA were at a similar level to that of Ang II AAA; and ii) the numbers of upregulated genes in three ER stress TF potential target genes in Ang II-ApoE-KO abdominal aorta upregulated more XBP1—IRE1 target genes and ATF6 target genes but less ATF4-PERK target genes than that of Ang II-ApoE-KO thoracic aorta (Figure 5E). Here, EIF2AK3 is linked to aneurysm.