AGT and aneurysm: As shown in Figure 5A, the 73 HPA ER localization protein genes, KEGG ER stress signaling genes, and ER stress regulator interactome genes were upregulated in PPE-induced aneurysms, and the 11 HPA ER genes, KEGG ER stress genes, and ER stress regulator interactome genes were upregulated in BAPN-Ang II-induced aneurysms.