These clusters comprised tumor cells expressing different levels of HLA-DR (Clusters 2 and 4), CD4+ and CD8+ T cells (Clusters 3 and 8), mononuclear phagocytes (MNPs) (Clusters 5, 6, and 7), and one cluster with low expression for all markers (Cluster 1) (Figure 6D). Here, CD8A is linked to neoplasm.