The ‘Toll‐like receptor cascades’, ‘cytokine signalling’, ‘activation of C3 and C5’, ‘FcγR activation’, ‘antimicrobial peptides’ and ‘dectin‐1 mediated non‐canonical NF‐κB signalling’ pathways were strongly activated in our sepsis patients, at times in several tissues. This evidence concerns the gene FCGR2A and Sepsis.