KEGG analysis showed that DEGs were highly enriched in the IL-17 signaling pathway (hsa04657), amoebiasis (hsa05146), ECM-receptor interaction (hsa04512), rheumatoid arthritis (hsa05323), staphylococcus aureus infection (hsa05150), and viral protein interaction with cytokine and cytokine receptor (hsa04061) (Fig. 7B and Supplementary Table S6). This evidence concerns the gene IL17A and rheumatoid arthritis.