The predominant cluster within medium and large clones from control mice was composed of CD8+ GZMB+ LAG3+ (p < 0.05) and CD8+ naïve (p < 0.01) T cells, whereas in MM bearing mice it was composed of CD8+ GZMK+ T cells (p < 0.05) (Fig. 3C, Supplementary Dataset 4). This evidence concerns the gene GZMK and Miyoshi myopathy.