TP53 and Miyoshi myopathy: Because large T cell clones showed co-expression of multiple immune checkpoints, the combined administration of anti-PD1 plus anti-LAG3 or anti-TIGIT was tested in immunocompetent C57BL/6 mice intravenously injected with the MM5080 murine MM cell line, which was established from BIcγ1 mice with an additional P53 deletion (Fig. S7).