CXCL8 and cystic fibrosis: Along the trajectory during the transition of cMo-2s to CF-enriched cMo-1s, CXCL8, INHBA and CXCL3 were highly expressed in cMo-1s and promoted adipogenesis and the inflammatory response (Fig. 5h and Supplementary Fig. 7i), and the levels of the corresponding proteins were increased in the plasma of CD patients who underwent surgery for small intestine stenosis and/or obstruction with CF hyperplasia (Fig. 5i).