As shown in Fig. 6A, high expression of PRELP in tumors correlated with a high number of tumor-infiltrating CD8+ T cells in skin cutaneous (HR = − 4.079, p = 1.25e−04) and metastatic melanoma (HR = − 3.758; p = 6.19e−04) (Fig. 6B). This evidence concerns the gene CD8A and metastatic melanoma.