Among fibroblast subgroups, FAP expression is higher in cells from CRPC samples (GSE137829) and PCa samples (GSE141445); among CAF subgroups, both FAP and TGFB1 expressions are higher in cells from CRPC samples (GSE137829) compared to cells from PCa samples (GSE141445 and GSE176031), suggesting an enhanced CAF conversion process in CRPC samples. The gene discussed is FAP; the disease is posterior cortical atrophy.