As it has been described that HB highly depends on MYC,5 and that proliferation of hepatocellular cancer cells that also express high levels of MYC could be abrogated by CDK9 gene silencing,33 it could be speculated that interference of the CDK9/MYC relationship underlies the molecular mechanism behind the effectiveness of both drugs in HB. This evidence concerns the gene MYC and hepatocellular carcinoma.