- Patients with infected wounds- Patients who are pregnant or breastfeeding- Patients with known concomitant medical conditions that may interfere with normal wound healing (eg, immune deficiency, HIV, uncontrolled diabetes, cancer, etc)- Known allergy to porcine collagen or elastin- Patients who are expected (according to the responsible medical doctor) to be nonadherent to the study protocol- Previous enrollment of the patient into the current study- Full-thickness skin wound located in face and/or genitals. The gene discussed is ELN; the disease is cancer.