In human cancer cell lines, ectopic CENP-A can be found at the PCAT2 locus, whereas, PCAT2 DNA is not known to position nucleosomes, in contrast to α-satellite DNA or the Widom 601-sequence (Lowary and Widom, 1998; Luger et al., 1997; Stormberg and Lyubchenko, 2022; Thåström et al., 1999). The gene discussed is CENPA; the disease is cancer.