The expression of genes encoding TNF receptors (Tnfrsf1b, Tnfrsf1a, and Tnfrsf10b), adhesion and leukocyte extravasation molecules (Esam, Icam1, Icam2, Mcam1, and Pecam1), apoptotic factors (Casp8 and Fas), proinflammatory factors (Il6ra, Il1r1, Ccl2, and Il6), and Toll-like receptors (TLRs) (Tlr1, Tlr13, Tlr7, and Tlr8) were downregulated in the brains of aged stroke mice after hNSC transplantation compared to those without hNSC transplantation. This evidence concerns the gene IL6 and Stroke.