Additionally, the evaluation of FAM134B expression in the human normal liver cell line HL7702 and HCC cell lines Hep3B and Huh7 demonstrated low levels of FAM134B expression in normal liver cells, whereas it was significantly upregulated in Hep3B and Huh7 HCC cell lines (p < 0.01, as shown in Figure 1A,B). The gene discussed is RETREG1; the disease is hepatocellular carcinoma.