In a DFE/DNCB induced murine dermatitis model, two flavonoids, Galangin and Rutin, were found to suppress IL-32 in lesional skin of these mice, which was associated with reduced clinical scores and lymphocyte proliferation, as well as lower serum IgE levels, highlighting the importance of IL-32 in inflammatory skin lesions (10, 11). Here, IL32 is linked to skin disorder.