Patient randomization, collection of baseline characteristics of the participants (age, body mass index, primary infertility/secondary infertility; infertility duration; cause of infertility, history of fertility treatment; past medical history; history of drug allergy; vital signs; physical examination; urine hCG test; electrocardiogram; basal FSH, LH, E2, PRL, T, P, AMH, AFC; blood routine; urine routine; blood biochemistry; coagulation function; blood type; hepatitis B, syphilis, HIV examination, etc.). This evidence concerns the gene PLOD1 and syphilis.