Consistent with this result, an immunoblot analysis showed that human/rat BC cells transfected with miR-145S1 strongly induced the activation of IFN-STAT1/2 signaling (the upregulation of p-STAT1/2 and STAT1/2; Figure 1H), albeit with weak effects on some cells treated with miR-145WT. Here, IFNA1 is linked to breast cancer.