PTBP1 and breast cancer: In addition, BiPLs with the low expression of miR-145 exhibited the significant upregulation of BC-related oncogenes (cyclin D1, Fascin∗, SOCS7∗, STAM∗, c-Myc∗, and PTBP1∗; ∗ indicates a direct target of miR-145) and a decreased level of a marker of IFN pathway activation (p-STAT1, Figures 6B and S8).