SMARCA4 and Peritoneal Fibrosis: Another valuable finding in this study is that MCL, a novel guaianolide sesquiterpene lactone semisynthesized from parthenolide [23, 24], prevents and ameliorates peritoneal fibrosis, as demonstrated in our study previously [27], through impeding BRG1 from recognizing and attaching to H3K14ac by binding to the N1540 of BRG1.