MORC3 and myositis disease: In 60–90% of patients with jDM, myositis-specific antibodies, such as anti-TIF 1-γ (p155), anti-NXP2/(p140/MJ), anti-MDA5, as well as myositis-associated antibodies, such as anti-La (‘SSB’), anti-Ro (‘SSA’), and anti-Sm, can be detected and helpful in establishing the diagnosis [6, 7].