Within this group, we observed increased ribosomal-association of transcripts modulating synaptic transmission (AKAP12, DNM1, GRIN2D, GSK3B, HOMER1, HTR1A, LGI1, NF1, PICK1, PLCG1, RAB8A, RAPSN) and decreased ribosomal-association transcripts coding for regulators of translation (CPEB1, EEF2K, EIF2B2, EIF2S1, EIF4E) as well as memory impairment (BDNF, DPYSL2, DRD1, DRD2, FYN, NGFR, NOS1, PTEN, SYN1, VPS35). The gene discussed is PICK1; the disease is memory impairment.