To further verify our analysis results, immunostaining of YTHDF3 in TC (including papillary thyroid carcinoma (PTC), follicular thyroid carcinoma (FTC), medullary thyroid carcinoma (MTC), and anaplastic thyroid carcinoma (ATC)) and normal thyroid tissues were displayed in Fig. 6A, which proved that compared with normal tissues, YTHDF3 was up-regulated in TC. This evidence concerns the gene YTHDF3 and thyroid gland undifferentiated (anaplastic) carcinoma.