Moreover, we detected 9q21.3 (CDKN2A and CDKN2B) deletion in all cases with elevated and reduced expression of CMTM6, but the G score of elevated expression cohort was greatly greater in elevated cohort than that of reduced CMTM6 expression cohort within PAAD (Fig. 3F, G). Here, CDKN2A is linked to pancreatic adenocarcinoma.