CMTM6 and neoplasm: It may interact with chemokines, adhesion molecules, or other immune cell regulators to modulate the composition and function of TILs, influencing the overall anti-tumor immune response; (4) interplay with other immune regulatory pathways: CMTM6 may also interact with various immune regulatory pathways, such as cytokine signaling, NF-κB pathway, or T-cell co-stimulatory pathways, to shape the immune landscape in the TME.