A total of 25 networks were constructed by IPA and the one with the highest score is shown in Fig. 2B. This particular network shows 34 gene products with different levels in CDH and control amniotic fluids that work together in cardiovascular system development and function, connective tissue disorders and dermatological diseases and conditions; all proteins associated with this network were identified in our dataset and their expression ratios are overlaid. Here, CHDH is linked to connective tissue disorder.