Interestingly, Krt5-immunoreactive pods observed in lungs of either IL-22 LOF or IL-22r cLOF mice 14 days post-PR8 infection displayed evidence for Scgb3a2 expression that was absent in comparable Krt5-immunoreactive pod structures of wildtype control mice (Fig. 6G). This evidence concerns the gene SCGB3A2 and infection.