In contrast, inactivation of ABCC1 had no impact on cell proliferation in multiple AML cell lines in the absence of drugs, which is in line with previous data68, and ABCC1 inhibition did not sensitize AML cells to various other anticancer drugs that are used to treat AML, including the chemotherapeutic Cytarabine, FLT3-inibitors and IDH inhibitors. The gene discussed is IDH1; the disease is acute myeloid leukemia.