After GZ-R6 infection of HAE, IL-6 and IL-1b significantly increased at both sides during the early infection stage at 2 d.p.i., and then decreased rapidly (Figure 6A); however, IL-8, CD106, IL-2, CD54, IFN-γ, IL-4, CCL5, TNF-α and IL-10 showed significant increases only at the basolateral sides at different infection times, and no differences were observed at the apical side (Figure 6B). This evidence concerns the gene IL2 and infection.