APOE and atherosclerosis: Acknowledging the prominent underlying role of inflammation in the initiation and progression of vascular disease, and the numerous anti-inflammatory roles ascribed to Tβ4 [37], [38], [39], we characterised the inflammatory responses of Tβ4-/Y; ApoE-/- and Tβ4+/Y; ApoE-/- mice during atherosclerosis.